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What do we know about the relationships between preconception parental health, infertility, and pregnancy outcomes?

What do we know about the relationships between preconception parental health, infertility, and pregnancy outcomes?
Until recently, research on parental health in humans has focused largely on associations with fertility measures and pregnancy. With the exception of maternal diabetes mellitus and obesity, those studies that extend to infant outcomes most commonly involved maternal exposures to environmental or pharmaceutical toxins. The effects of paternal exposures and health on infant outcomes are much less studied than maternal effects. Work in experimental and domestic species has demonstrated that preconception parental health can affect pregnancy outcomes and offspring characteristics, even across multiple generations.
Source: fertstert.org

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