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To suppress or not to suppress? If that is the question, has it been answered?

To suppress or not to suppress? If that is the question, has it been answered?
The administration of prolonged courses of GnRH agonists (GnRH-a) before initiating ovarian stimulation has been shown by multiple investigators to enhance pregnancy rates in endometriosis patients who are undergoing in vitro fertilization (IVF) (1). A Cochrane database analysis of three prospective randomized trials including 163 patients with varying stages of endometriosis who received 3–6 months of prestimulation GnRH-a showed significantly higher clinical pregnancy (odds ratio [OR] 4.28, 95% confidence interval [CI] 2.0–9.15) and live birth (OR 9.1, 95% CI 1.08–78.2) rates compared with women with endometriosis who did not receive prolonged agonist therapy (2).
Source: fertstert.org

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