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Preimplantation genetic screening (PGS) in egg donor (ED) cycles: is it a valid option?

Preimplantation genetic screening (PGS) in egg donor (ED) cycles: is it a valid option?
A recent study demonstrates a high variability among different centers in the euploidy rate of embryos generated from donated eggs (Munnè et al., 2017). Using SNP array analysis, most embryonic meiotic aneuploidies have been found to be from maternal origin. From these observations, it may be speculated that the ovarian stimulation may affect the embryo euploidy rate independently from the oocyte source. Despite this, PGS in ED cycles is often considered unnecessary. Very few studies examined the use of PGS in ED cycles thus far and the results were inconclusive.
Source: fertstert.org

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