Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids

Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids
Uterine fibroids (UFs; also known as leiomyomas) are the most common benign neoplastic threat to women’s health in U.S. and worldwide, with annual health care costs estimated in the hundreds of billions of dollars. UF-caused morbidities negatively impacts women of all ethnicities, but disproportionately affect African-American women, who have a 3- to 4-fold higher incidence rate and relative risk of UFs than Caucasian women. These tumors can grow and cause severe adverse health outcomes such as excessive vaginal bleeding, pelvic pain, as well as urinary and bowel compression with a major negative effects on women’s quality of life (1).
Source: fertstert.org