Fertility preservation in girls with Turner syndrome: limitations, current success and future prospects

Fertility preservation in girls with Turner syndrome: limitations, current success and future prospects
In this issue of the Fertility and Sterility, Dr. Mamsen and a distinguished group of scientists report a multicenter, retrospective, case-control study exploring the feasibility of ovarian tissue cryopreservation in girls with Turner syndrome (TS) (1). Consistent with previous studies, they find that detectable serum antimüllerian hormone (AMH) levels, normal serum follicle-stimulating hormone (FSH) levels, and mosaic karyotype are predictors of the presence of primordial follicles. In 7 (78%) of 9 cases of ovaries where follicles were found, the follicle densities were within 95% of the controls, their mean was lower than in age-matched controls, and the sample size was too small for a robust comparison.
Source: fertstert.org