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Artificial intelligence and the diagnosis of abnormal pregnancy: single nucleotide polymorphism away

Artificial intelligence and the diagnosis of abnormal pregnancy: single nucleotide polymorphism away
In a recent retrospective analysis by Maisenbacher et al. (1), the examination of products of conception (POCs) by single nucleotide polymorphism (SNP) array was used to determine the frequency of molar pregnancy in miscarriage. For the cohort of miscarriages where complete history and clinical findings were available, complete and partial molar pregnancies had a much higher detection rate by genetic analyses than by traditional ultrasound and histopathology. This strategy in using high-resolution chromosomal microarray analysis (CMA) as the preferred technology in the genetic evaluation allows the authors to focus on the detection of triploidy and isodisomic- and heterodiscomic-full paternal uniparental disomy (UPD) with SNP array technology.
Source: fertstert.org

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