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Premature progesterone elevation: targets and rescue strategies

Premature progesterone elevation: targets and rescue strategies
Progesterone elevation during the late follicular phase of ovarian stimulation for in vitro fertilization negatively impacts the assisted reproductive technology-outcome. The evidence available supports an advanced endometrial maturation and a direct negative effect on its receptivity. On the other hand, some retrospective analysis suggests an impairment of oocyte and embryo quality. Recent publications confirm that enhanced follicle-stimulating hormone–stimulation towards the end of the follicular phase of ovarian stimulation is the main course of progesterone elevation.
Source: fertstert.org

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