Revisiting the relationship between vitamin D and ovarian reserve

Revisiting the relationship between vitamin D and ovarian reserve
Vitamin D plays a crucial role in maintaining calcium homeostasis and bone density within the human body. Its biologic actions are mediated via the vitamin D receptor, most commonly found in calcium-regulating tissues such as the bones and parathyroid glands (1). However, the identification of vitamin D receptors in reproductive organs such as the ovary, endometrium, testis, hypothalamus, and pituitary has fueled an ongoing interest about the role of vitamin D in human reproduction (1). Prior studies have demonstrated that vitamin D can alter anti-müllerian hormone (AMH) signaling, follicle stimulating hormone (FSH) sensitivity and progesterone (P) production and release in human granulosa cells (1).
Source: fertstert.org