In vitro fertilization and infertility do not cause a significant alteration in placental gene expression at the end of the first trimester

In vitro fertilization and infertility do not cause a significant alteration in placental gene expression at the end of the first trimester
Pregnancies achieved after fertility treatments are associated with an increased risk of adverse outcomes such as compromised placentation, perinatal complications, and birth defects (1, 2). Moreover, studies using animal models indicate that assisted reproductive technology (ART) procedures could alter the epigenetic landscape of the preimplantation embryo when compared with embryos conceived naturally (3). These data lead to significant concerns regarding the safety of ART and therefore the health and well-being of individuals conceived using these technologies.
Source: fertstert.org